Research into biopolymerisation and the use of bio-available molecules as monomers provides a mechanism to produce polymers which biodegrade back into natural compounds rather than producing microplastic waste associated with petroleum-chemical based polymers. This is biological process is supported through fundamental research in polymer chemistry.
Microplastic pollution is a major global issue with particles of waste plastic being found throughout the natural environment to the extent that they have been even in the deepest parts of our oceans. Legislation can only go so far in reducing the extent of polymers and plastics as they form such an integral part of modern life.
The direction of our polymer research is aimed at the use of molecules which are found in nature (e.g. gamma-glutamic acid) as the monomers from which can be made. These polymers once formed and used, decompose back to molecules rather than breaking down into small plastic fragments. Moreover to further enhance sustainability we are investigating biological processing to create and decompose these biopolymers.
Our successes in this area have led to a local cosmetic manufacturer replacing the petrochemically based polymer glitter used in some products with a biodegradable alternative.
For REF 2021 an Impact Case Study was submitted from this group focusing on how novel environmentally friendly products have been used by industrial partners in the commercial cleaning and cosmetic sectors, as well as used to inform national policy decision at UK Parliament.
Explore The Polymer Science Group
- Zięba, M.; Włodarczyk, J.; Gupta, A.; Pastusiak, M.; Chaber, P.; Janeczek, H.; Musioł, M.; Sikorska, W.; Kaczmarczyk, B.; Radecka, I.; Kowalczuk, M.; Savickas, A.; Savickiene, N.; Adamus, G., Bioresorbable electrospun mats of poly(D, L)-lactide / poly[(R, S)-3-hydroxybutyrate] blends for potential use in the treatment of difficult-to-heal skin wounds. European Polymer Journal 2021, 147, 110334-110334. publisher: https://doi.org/10.1016/j.eurpolymj.2021.110334; open access: https://wlv.openrepository.com/handle/2436/623933
- Swingler, S.; Gupta, A.; Gibson, H.; Kowalczuk, M.; Heaselgrave, W.; Radecka, I., Recent advances and applications of bacterial cellulose in biomedicine. Polymers 2021, 13 (3), 412-412. publisher: https://doi.org/10.3390/polym13030412; open access: https://wlv.openrepository.com/handle/2436/623911
- Naguib, M.; Rashed, A.; Keddie, D., Self-healing polymers synthesized by Ring Opening Metathesis Polymerization (ROMP) of bio-derived furanic molecules. Journal of Materials Science 2021, 56, 8900-8909. publisher: https://doi.org/10.1007/s10853-021-05853-x; open access: https://wlv.openrepository.com/handle/2436/623911
- Pasaribu, K. M.; Gea, S.; Ilyas, S.; Tamrin, T.; Radecka, I., Characterization of bacterial cellulose-based wound dressing in different order impregnation of chitosan and collagen. Biomolecules 2020, 10 (11), 1511-1511. publisher: https://doi.org/10.3390/biom10111511; open access: https://wlv.openrepository.com/handle/2436/623771
- Musioł, M.; Jurczyk, S.; Sobota, M.; Klim, M.; Sikorska, W.; Zięba, M.; Janeczek, H.; Rydz, J.; Kurcok, P.; Johnston, B.; Radecka, I., (Bio)degradable polymeric materials for sustainable future—Part 3: Degradation studies of the PHA/wood flour-based composites and preliminary tests of antimicrobial activity. Materials 2020, 13 (9), 2200 - 2200. publisher: https://doi.org/3390/ma13092200; open access: https://wlv.openrepository.com/handle/2436/623214
- Khan, H.; Kaur, S.; Baldwin, T. C.; Radecka, I.; Jiang, G.; Bretz, I.; Duale, K.; Adamus, G.; Kowalczuk, M., Effective control against broadleaf weed species provided by biodegradable PBAT/PLA mulch film embedded with the herbicide 2-methyl-4-chlorophenoxyacetic acid (MCPA). ACS Sustainable Chemistry and Engineering 2020, 8 (13), 5360-5370. publisher: https://doi.org/10.1021/acssuschemeng.0c00991; open access: https://wlv.openrepository.com/handle/2436/623164
- Hayes, C. J.; Palframan, M. J.; Pattenden, G., The impact of macrocycle conformation on the taxadiene-forming carbocation cascade: insight gained from sobralene, a recently discovered verticillene isomer. Journal of Organic Chemistry 2020, 85 (6), 4507-4514. publisher: https://doi.org/1021/acs.joc.0c00369; open access: https://wlv.openrepository.com/handle/2436/623164
- Stace, S. J.; Vanderspikken, J.; Howard, S. C.; Li, G.; Muir, B. W.; Fellows, C. M.; Keddie, D. J.; Moad, G., Ab initio RAFT emulsion polymerization mediated by small cationic RAFT agents to form polymers with low molar mass dispersity. Polymer Chemistry 2019, 10, 5044-5051. publisher: https://doi.org/1039/c9py00893d; open access: https://wlv.openrepository.com/handle/2436/622634
- Palframan, M.; Pattenden, G., Biosynthetic interrelationships within polycyclic cembranoids isolated from corals: conjecture, biomimetic synthesis and reality. European Journal of Organic Chemistry 2019, 2020 (16), 2330-2349. publisher: https://doi.org/1002/ejoc.201901438; open access: https://wlv.openrepository.com/handle/2436/623041
- Palframan, M.; Bandi, K.; Hamilton, J.; Pattenden, G., Acid-catalysed rearrangement of the sandfly pheromone sobralene to verticillenes, consolidating its relationship inter alia to the taxanes and phomactins. Synlett 2019, 30 (16), 1899-1903. publisher: https://doi.org/1055/s-0039-1690131; open access: https://wlv.openrepository.com/handle/2436/623038
- Gupta, A.; Keddie, D.; Kannappan, V.; Gibson, H.; Khalil, I.; Kowalczuk, M.; Martin, C.; Shuai, X.; Radecka, I., Production and characterisation of bacterial cellulose hydrogels loaded with curcumin encapsulated in cyclodextrins as wound dressings. European Polymer Journal 2019, 118, 437 - 450. publisher: https://doi.org/1016/j.eurpolymj.2019.06.018; open access: https://wlv.openrepository.com/handle/2436/622532
- Tselepy, A.; Schiller, T. L.; Harrisson, S.; Guerrero-Sanchez, C.; Moad, G.; Keddie, D. J., Effect of scandium triflate on the RAFT copolymerization of methyl acrylate and vinyl acetate controlled by an acid/base “switchable” chain transfer agent. Macromolecules 2018, 51 (2), 410-418. publisher: https://doi.org/1021/acs.macromol.7b02104; open access: https://wlv.openrepository.com/handle/2436/621110
- Stace, S. J.; Fellows, C. M.; Moad, G.; Keddie, D. J., Effect of the Z- and Macro-R-Group on the thermal desulfurization of polymers synthesized with acid/base "switchable" dithiocarbamate RAFT agents. Macromolecular Rapid Communications 2018, 39 (19), 1800228. publisher: https://doi.org/1002/marc.201800228; open access: https://wlv.openrepository.com/handle/2436/621602
- Naguib, M.; Schiller, T. L.; Keddie, D. J., Rapid, regioselective living ring-opening metathesis polymerization of bio-derivable asymmetric tricyclic oxanorbornenes. Macromolecular Rapid Communications 2018, 39 (7), 1700794. publisher: https://doi.org/1002/marc.201700794; open access: https://wlv.openrepository.com/handle/2436/621111
- Gonzalez Ausejo, J.; Rydz, J.; Musioł, M.; Sikorska, W.; Sobota, M.; Włodarczyk, J.; Adamus, G.; Janeczek, H.; Kwiecień, I.; Hercog, A.; Johnston, B.; Khan, H. R.; Kannappan, V.; Jones, K. R.; Morris, M. R.; Jiang, G.; Radecka, I.; Kowalczuk, M., A comparative study of three-dimensional printing directions: The degradation and toxicological profile of a PLA/PHA blend. Polymer Degradation and Stability 2018, 152, 191-207. publisher: https://doi.org/1016/j.polymdegradstab.2018.04.024; open access: https://wlv.openrepository.com/handle/2436/621410
- Sillero, J.; Rojas-Molina, M.; Emeran, A.; Kharrat, M.; Winkler, J.; Khan, H.; Flores, F.; Rubiales, D., Identification and multi-environment validation of resistance to rust (Uromyces viciae-fabae) in Vicia faba. Crop and Pasture Science 2017, 68 (10-11), 1013-1023. publisher: https://doi.org/1071/cp17099; open access: https://wlv.openrepository.com/handle/2436/622789
- Kwiecień, I.; Adamus, G.; Jiang, G.; Radecka, I.; Baldwin, T. C.; Khan, H. R.; Johnston, B.; Pennetta, V.; Hill, D.; Bretz, I.; Kowalczuk, M. M., Biodegradable PBAT/PLA blend with bioactive MCPA-PHBV conjugate suppresses weed growth. Biomacromolecules 2017, 19 (2), 511-520. publisher: https://doi.org/1021/acs.biomac.7b01636; open access: https://wlv.openrepository.com/handle/2436/621024
- Palframan, M.; Alharthy, R.; Powalowska, P.; Hayes, C., Synthesis of triazole-linked morpholino oligonucleotides via CuI catalysed cycloaddition. Organic & Biomolecular Chemistry 2016, 14 (11), 3112-3119. publisher: https://doi.org/1039/c6ob00007j; open access: https://wlv.openrepository.com/handle/2436/623043
- Baldwin, T. C.; Williams, P.; Gashua, I. B., Molecular characteristics, association and interfacial properties of Gum Arabic harvested from both Acacia Senegal and Acacia seyal. Food Hydrocolloids 2016, 61, 514-522. publisher: https://doi.org/1016/j.foodhyd.2016.06.005; open access: https://wlv.openrepository.com/handle/2436/612493
- Gashua, I. B.; Williams, P. A.; Yadav, M. P.; Baldwin, T. C., Characterisation and molecular association of Nigerian and Sudanese Acacia gum exudates. Food Hydrocolloids 2015, 51, 405-413. publisher: https://doi.org/1016/j.foodhyd.2015.05.037; open access: https://wlv.openrepository.com/handle/2436/604212